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Jump toArticleAbstractThe Pathophysiology of Chronic CADThe Therapy of Chronic CAD: Perspective for the FutureThe Pathophysiology of the ACSThe Vulnerable Plaque: Fact or Fancy?Treatment of the ACS: Perspective on the FutureConclusions and Clinical ImplicationsAcknowledgmentsReferencesFigures & TablesInfo & MetricseLetters. Subscribe My Account BMA members Personal subscribers My email alerts BMA member login Login Username * Password * Forgot your sign in details? Need to activate BMA members Sign in via OpenAthens Sign in via your institution Edition: International US UK South Asia Toggle navigation The BMJ logo Site map Search Search form SearchSearch Advanced search Search responses Search blogs Toggle top menu ResearchAt a glance Research papers Research methods and reporting Minerva Research news EducationAt a glance Clinical reviews Practice Minerva Endgames State of the art News & ViewsAt a glance News Features Editorials Analysis Observations Head to head Editor's choice Letters Obituaries Views and reviews Rapid responses Campaigns Archive For authors Jobs Hosted Education Pathophysiology and. This site uses cookies. We are sorry, but an unhandled error occurred. Cookies are required to use this site.

Related ArticlesNo related articles found.Web of Science PubMed Google Scholar . More info Close By continuing to browse the site you are agreeing to our use of cookies. We'll be back as soon as we can! We're sorry for the inconvenience.. Submit Request Permissions . Pathophysiology and investigation of coronary artery disease BMJ 2003; 326 :1027 BibTeX (win & mac)Download EndNote (tagged)Download EndNote 8 (xml)Download RefWorks Tagged (win & mac)Download RIS (win only)Download MedlarsDownload Help If you are unable to import citations, please contact technical support for your product directly (links go to external sites): EndNote ProCite Reference Manager RefWorks Zotero Request permissions Author citationArticles by Ever D Grech Add article to BMJ Portfolio Email to a friendForward this page Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. 403 Forbidden . Cited By.RRM1, RRM2 and ERCC2 Gene Polymorphisms in Coronary Artery DiseaseUtility of {gamma}-Glutamyl Transferase in Predicting Troponin Elevation in Emergency DepartmentsAndrogen deprivation therapy and cardiovascular disease: what is the linking mechanism?Apelin: an antithrombotic factor that inhibits platelet functionmiRNA 206 and miRNA 574-5p are highly expression in coronary artery diseaseSerum Cystatin C and the Risk of Coronary Heart Disease in Ethnic Chinese Patients With Normal Renal FunctionScreening for suspected coronary heart disease in patients, using integrated serum biochemical indicesAcute Coronary Syndrome: Focus on Antiplatelet TherapyIdentifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsNeutrophil to Lymphocyte Ratio and the Extent of Coronary Artery Disease: Results From a Large Cohort StudyEffects of Rivaroxaban on Platelet Activation and Platelet-Coagulation Pathway Interaction: In Vitro and In Vivo StudiesRequiem for the 'vulnerable plaque'ABO Blood Group as a Model for Platelet Glycan Modification in Arterial ThrombosisA Risk Score Derived from the Analysis of a Cluster of 27 Serum Inflammatory Cytokines to Predict Long Term Outcome in Patients with Acute Myocardial Infarction: a Pilot StudyInflammation modulation and cardiovascular disease preventionEffect of CPAP on Endothelial Function in Subjects With Obstructive Sleep Apnea: A Meta-AnalysisAcute Coronary SyndromeRole of Flow-Sensitive microRNAs in Endothelial Dysfunction and Atherosclerosis: Mechanosensitive Athero-miRsSupervision of Exercise Testing by Nonphysicians: A Scientific Statement From the American Heart AssociationRelationship between early postoperative C-reactive protein elevation and long-term postoperative major adverse cardiovascular and cerebral events in patients undergoing off-pump coronary artery bypass graft surgery: a retrospective studyAspirin Therapy in Primary Cardiovascular Disease Prevention: A Position Paper of the European Society of Cardiology Working Group on ThrombosisInduction of T helper 2 responses against human apolipoprotein B100 does not affect atherosclerosis in ApoE-/- miceRadial artery intima-media thickness predicts major cardiovascular events in patients with suspected coronary artery diseaseAntiplatelet and Anticoagulation Therapy for Acute Coronary SyndromesInflammation and its Resolution as Determinants of Acute Coronary SyndromesSystemic inflammation and brachial artery endothelial function in the Multi-Ethnic Study of Atherosclerosis (MESA)Involvement of fibrinolytic regulators in adhesion of monocytes to vascular endothelial cells induced by glycated LDL and to aorta from diabetic miceLong-term exposure to traffic-related air pollution and progression of carotid artery atherosclerosis: a prospective cohort studyIdentifying Common Genetic Variants in Blood Pressure Due to Polygenic Pleiotropy With Associated PhenotypesUpdate on platelet glycoprotein IIb/IIIa inhibitors: recommendations for clinical practiceNovel Direct-Acting Anticoagulants for Risk Reduction in ACSCan We Measure How Hot the Plaque Is? Not Yet, But.Update on acute coronary syndromes: the pathologists' viewInflammatory Biomarkers, Death, and Recurrent Nonfatal Coronary Events After an Acute Coronary Syndrome in the MIRACL StudyCharacteristics of aortic wall extracellular matrix in patients with acute myocardial infarction: tissue microarray detection of collagen I, collagen III and elastin levelsComputed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary StenosisThe role of hypoxia-inducible factor 1 in atherosclerosisClinical Utility of Genetic Variants for Cardiovascular Risk Prediction: A Futile Exercise or Insufficient Data?Decoy Receptor 3, a Novel Inflammatory Marker, and Mortality in Hemodialysis PatientsAssessment of subclinical atherosclerosis by carotid intima media thickness: technical issuesArginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and AtherogenesisOxidatively Modified Low Density Lipoprotein (LDL) Inhibits TLR2 and TLR4 Cytokine Responses in Human Monocytes but Not in MacrophagesProteomic profiling of acute coronary thrombosis reveals a local decrease in pigment epithelium-derived factor in acute myocardial infarctionInorganic nitrate: a major player in the cardiovascular health benefits of vegetables?Nonhuman Primates and other Animal Models in Diabetes ResearchAssociation of Long-term Exposure to Community Noise and Traffic-related Air Pollution With Coronary Heart Disease MortalityHigh Levels of Costimulatory Receptors OX40 and 4-1BB Characterize CD4+CD28null T Cells in Patients With Acute Coronary SyndromeIs a Myocardial Infarction More Likely to Result From a Mild Coronary Lesion or an Ischemia-Producing One?In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticlesChronic Stress, Immune Dysregulation, and HealthIs arterial wall-strain stiffening an additional process responsible for atherosclerosis in coronary bifurcations?: an in vivo study based on dynamic CT and MRI2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular SurgeryInsulin treatment attenuates diabetes-increased atherosclerotic intimal lesions and matrix metalloproteinase 9 expression in apolipoprotein E-deficient miceAssociation Between Depression and Inflammation--Differences by Race and Sex: The META-Health StudyInhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-IPreoperative cardiac management of the patient for non-cardiac surgery: an individualized and evidence-based approachMechanism of beneficial effects of physical activity on atherosclerosis and coronary heart diseaseThe power of Pasteur's quadrant: cardiovascular disease at the turn of the centuryInvited Commentary: Discrimination--An Emerging Target for Reducing Risk of Cardiovascular Disease?Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary DiseaseCRP enhances soluble LOX-1 release from macrophages by activating TNF-{alpha} converting enzymeHigh-sensitivity C-reactive protein and clopidogrel treatment in patients at high risk of cardiovascular events: a substudy from the CHARISMA trialExposure to occupational noise and cardiovascular disease in the United States: the National Health and Nutrition Examination Survey 1999-2004Proteinase 3 and prognosis of patients with acute myocardial infarctionImpact of soluble fms-like tyrosine kinase-1 and placental growth factor serum levels for risk stratification and early diagnosis in patients with suspected acute myocardial infarctionThe Same Chromosome 9p21.3 Locus Is Associated With Type 2 Diabetes and Coronary Artery Disease in a Chinese Han PopulationEffects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical PerspectivesCandidate Genes and Mechanisms for 2-Methoxyestradiol-Mediated VasoprotectionUtilization of Secondary Prevention Therapies in Patients With Nonobstructive Coronary Artery Disease Identified During Cardiac Catheterization: Insights From the National Cardiovascular Data Registry Cath-PCI RegistryPKC{zeta} decreases eNOS protein stability via inhibitory phosphorylation of ERK5Circulating MicroRNAs As Potential Biomarkers of Coronary Artery Disease: A Promise to Be Fulfilled?CrossRef This article has not yet been cited by articles in journals that are participating in CrossRef Cited-by Linking. The connective tissue matrix is derived from smooth muscle cells, which migrate from the media into the intima, where they proliferate and change their phenotype to form a fibrous capsule around the lipid core. This Issue Circulation June 28, 2005, Volume 111, Issue 25 Table of Contents Previous ArticleNext Article . Some suggestions: Go back to the last page Go to the home page ..

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